Product ID:GLUTATHIONE, REDUCED, FREE ACID, 3541
MSDS Date:03/31/1999
FSC:6505
NIIN:00N092486
Status Code:A
MSDS Number: CJTCY

Emergency Phone: 800-424-9300

Info Phone: 800-854-3417

Cage: 29089

Telephone: 619-450-5558; 800-854-3417

Cage: 29089

GLUTATHIONE, REDUCED

CAS: 70-18-8

RTECS: MC0556000

LD50 LC50 Mixture:LD50: (ORAL,RAT) 1250 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE HARMFUL BY INGESTION,
INHALATION OR ABSORPTION THROUGH SKIN. CHRONIC: THERE IS LIMITED
EVIDENCE THAT GLUTATHIONE, REDUCED, FREE ACID IS MUTAGENIC IN
LABORATORY CELL CULTURES. UNTIL FURTH ER TESTING HAS BEEN DONE, IT
SHOULD BE TREATED AS A POSSIBLE MUTAGEN IN HUMANS.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:IN CASE OF SKIN CONT, WASH W/COPIOUS AMTS OF WATER FOR AT LST
15 MINUTES. REMOVE CONTAMD CLOTHING & SHOES AND WASH BEFORE
WEARING. CONSULT PHYSICIAN. IN CASES OF EYE CONT: FLUSH W/COPIOUS
AMTS OF WATE R FOR AT LST 15 MINUTES. ASSURE ADEQUATEFLUSHING BY
SEPARATING EYELIDS WITH FINGERS. CONSULT PHYSICIAN. IN CASES OF
INHALATION, REMOVE TO FRESH AIR & MONITOR BREATHING. IF BRTHG
BECOMES DFCLT, GIVE OX YG & CONSULT PHYSICIAN. IF BRTHG STOPS, GIVE
ARTF RESP & CONSULT PHYSICIAN. IN CASES OF INGESTION, WASH MOUTH
OUT W/WATER & CONSULT LOCAL POISON CENTER & PHYSICIAN.

Extinguishing Media:DRY CHEMICL POWDER, CARBON DIOXIDE, WATER SPRAY,
ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN
AND EYES.
Unusual Fire/Explosion Hazard:UPON THERMAL DECOMPOSITION, IT MAY EMIT
TOXIC GASES.

Spill Release Procedures:EVACUATE AREA. WEAR NIOSH APPRVD RESPIRATOR,
CHEMICAL SAFETY GOGGLES, RUBBER BOOTS, & HEAVY RUBBER GLOVES. SWEEP
UP & PLACE IN SUITABLE CONTAINER. AVOID RAISING DUST. HOLD FOR
APPROP DISPOSAL. WASH SP ILL & VENTILATE AREA AFTER MATERIAL PICKUP
IS COMPLETE.

Handling and Storage Precautions:STORE IN A TIGHTLY CLOSED CONTAINER IN
A +4C REFRIGERATOR. HYROSCOPIC. POSSIBLE MUTAGEN. AVOID CONTACT
WITH MATERIAL.
Other Precautions:AVOID PROLONGED OR REPEATED EXPOSURE. LAB SHOULD BE
EQUIPPED WITH SAFETY SHOWER AND AN EYE WASH STATION. WASH
THOROUGHLY AFTER HANDLING MATERIAL.

Respiratory Protection:USE A NIOSH APPROVED RESPIRATOR.
Ventilation:HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves:CHEMICAL RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER .
WEAR SUITABLE PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING MATERIAL.
Supplemental Safety and Health
SOL IN H*2O: SOLUBLE IN DMSO, ETHANOL, & WATER. TOX INFO: LNG;HAM;DOSE:
1 MMOL/L CYTOGENETIC ANALYSIS 1985. CELL BIOLOGY & TOX. 1(3), 123.
OVR;HAM;DOSE: 1 MMOL/L CYTOGENETIC ANALYSIS 1978. CANCER LETT ERS.
5, 199. LNG;HAM;DOSE: 1 MMOL/L SISTER CHROMATID EXCHANGE 1985. CELL
BIOLOGY & TOX. 193), 123. (OTHER INFO)

Solubility in Water:SUPDAT
Appearance and Odor:WHITE SOLID. PACKAGED UNDER AN INERT GAS.

Stability Indicator/Materials to Avoid:YES
NOT APPLICABLE.
Stability Condition to Avoid:STABLE UNDER NORMAL HANDLING PROCEDURES.
Hazardous Decomposition Products:UPON THERMAL DECOMPOSITION, MAY EMIT
TOXIC GASES INCLUDING CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN
OXIDES AND SULFUR OXIDES.

Waste Disposal Methods:COUNTRY, FEDERAL, STATE, AND LOCAL REGULATIONS
ARE VARIED AND CHANGE FREQUENTLY. FOR THIS REASON, WE RECOMMEND
THAT YOU CONTACT YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR
INFORMATION ON THE DISPOSAL OF THIS PRODUCT OR ARRANGE FOR
DISPOSAL BY A LICENSED DISPOSAL COMPANY.

Toxicological Information:RTECS NO: MC0556000. TOX DATA & REFERENCES:
ORL; MUS; LD50: 5 G/KG 1972. 'MODERN PHARMACEUTICALS OF JAPAN, IV,'
TOKYO JAPAN PHARMACEUTICAL, MEDICAL AND DENTAL SUPPLY EXPORTERS'
ASSOC. -, 93. IVN;MUS;L D50: 2238 MG/KG 1985. JANPANESE JOURNAL OF
ANTIBIOTICS. 38, 137. REPRO EFTS & REFERENCES: ORL;RAT;DOSE: 1250
MG/KG POST-IMPLANATION MORTALITY 1962. AMERICAN JOURNAL OF ANATOMY.
110,29. GENETIC DATA RE FERENCES: FBR;HMN;DOSE: 1 MMOL/L UNSCHEDULE
DNA SYNTHESIS 1978. CANCER LETTERS. 5,199. LVR;RAT:DOSE: 1 MMOL/L
DNA INHIBITION 1975. ARCHIVES OF BIOCHEMISTRY & PHYSICS. 166, 400.
(SUPDAT)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:NO INFORMATION FOUND.

Transport Information:UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA
CLASS: N/A. IATA PACKING GROUP: N/A.

Federal Regulatory Information:XN. RISK PHRASES: R40: POSSIBLE RISK OF
IRREVERSIBLE EFFECTS. SAFETY PHRASES: S22: DO NOT BREATH DUST.
S24/25: AVOID CONTACT WITH SKIN AND EYES. S36/37/39: WEAR SUITABLE
PROTECTIVE CLOTHING, GLOVES AN D EYE/FACE PROTECTION. S45: IN CASE
OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY.